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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
9.7
Human Site:
S189
Identified Species:
15.24
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S189
P
A
E
F
Q
G
A
S
Q
R
C
L
Q
L
G
Chimpanzee
Pan troglodytes
XP_510301
627
67581
D168
L
Q
H
P
V
D
S
D
S
N
L
F
S
H
L
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S189
P
A
E
F
Q
G
A
S
P
R
C
L
Q
L
G
Dog
Lupus familis
XP_544614
968
105825
T476
P
T
E
F
Q
G
A
T
Q
R
C
L
Q
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
Q190
A
E
F
Q
G
A
S
Q
R
C
L
Q
Q
L
G
Rat
Rattus norvegicus
Q62829
544
60692
D85
H
T
I
H
V
G
F
D
A
V
T
G
E
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
D180
F
R
G
D
P
L
R
D
Q
H
G
G
R
A
G
Chicken
Gallus gallus
XP_426393
667
74767
D189
P
S
E
F
Q
D
A
D
S
S
C
L
Q
R
A
Frog
Xenopus laevis
NP_001082100
650
73749
R184
P
K
D
I
P
E
K
R
G
P
R
S
H
E
K
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
P189
S
M
S
C
L
D
G
P
L
P
P
H
P
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
S180
T
P
G
V
G
G
A
S
S
G
G
F
K
P
P
Honey Bee
Apis mellifera
XP_001122147
624
70155
A165
L
D
K
L
R
Q
N
A
S
N
V
T
S
G
L
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
P113
K
Q
E
Q
Q
Q
N
P
Q
A
V
L
D
A
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
P340
T
A
L
R
I
S
T
P
Y
N
A
K
H
I
H
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
E338
K
P
L
I
S
A
P
E
N
P
V
H
V
T
H
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
0
93.3
86.6
N.A.
20
6.6
N.A.
13.3
53.3
6.6
0
N.A.
20
0
26.6
N.A.
P-Site Similarity:
100
6.6
93.3
93.3
N.A.
33.3
13.3
N.A.
20
60
13.3
0
N.A.
26.6
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
0
0
0
14
34
7
7
7
7
0
0
20
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
7
27
0
0
0
0
% C
% Asp:
0
7
7
7
0
20
0
27
0
0
0
0
7
0
0
% D
% Glu:
0
7
34
0
0
7
0
7
0
0
0
0
7
7
0
% E
% Phe:
7
0
7
27
0
0
7
0
0
0
0
14
0
7
0
% F
% Gly:
0
0
14
0
14
34
7
0
7
7
14
14
0
7
34
% G
% His:
7
0
7
7
0
0
0
0
0
7
0
14
14
7
14
% H
% Ile:
0
0
7
14
7
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
14
7
7
0
0
0
7
0
0
0
0
7
7
0
7
% K
% Leu:
14
0
14
7
7
7
0
0
7
0
14
34
0
27
27
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
14
0
7
20
0
0
0
0
0
% N
% Pro:
34
14
0
7
14
0
7
20
7
20
7
0
7
7
7
% P
% Gln:
0
14
0
14
34
14
0
7
27
0
0
7
34
0
0
% Q
% Arg:
0
7
0
7
7
0
7
7
7
20
7
0
7
7
0
% R
% Ser:
7
7
7
0
7
7
14
20
27
7
0
7
14
0
0
% S
% Thr:
14
14
0
0
0
0
7
7
0
0
7
7
0
7
7
% T
% Val:
0
0
0
7
14
0
0
0
0
7
20
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _